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This condition is associated with abnormal proliferation of mast cells and their infiltration and accumulation in the skin (cutaneous mastocytosis) and/or in organs throughout the body (systemic mastocytosis) and or an increase reactivity to histamine

This is an outstanding example of what patient organizations actually can do and that they, through citizen science, potentially can make significant scientific discoveries potentially changing the lives of thousands. Drachmann hopes that this leads to more researchers considering patients lived experiences

Studies show it modulates over 4,000 human genes activating those associated with tissue repair and cellular energy, while suppressing genes linked to inflammation and cellular senescence (the "zombie cells" that accumulate in aged tissue and accelerate aging around them)

These infections are associated with adverse outcomes like human immunodeficiency virus (HIV) transmission risk, preterm birth, high susceptibility to infection of human papillomavirus (HPV), as well as higher probabilities of developing cervical, endometrial, and ovarian cancers as shown in Figure 1 (Ciberia et al., 2021)

It hits three receptors at once: GLP-1 (cuts appetite, slows stomach), GIP (improves insulin signaling), and glucagon (raises energy expenditure and fat mobilization)