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In all family members, the first transcript variant corresponds to the canonical variant

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Post- L-GSH supplementation, we found increased levels of IFN- in PBMCs ( Figure 5A ), increased levels of TNF- in plasma ( Figure 5C ) and PBMCs ( Figure 5D ), and increased levels of IL-2 in plasma ( Figure 5E ) and PBMCs ( Figure 5F ) when compared to before L-GSH supplementation

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Oxidative stress (inflammation) arises from an imbalance between reactive oxygen species (ROS) and protective antioxidants