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Tirzepatide BNF Drug Monograph
The 44% reduction in liver fat observed in Phase 2 trials is why Eli Lilly is running the entire SYNERGY trial program specifically for liver disease
The AMPLITUDE-O trial of efpeglenatide (HR = 0.93, 95%CI = 0.691.26) investigated 4,076 participants with T2DM and a history of CVD or at least one cardiovascular risk factor in addition to kidney disease (Gerstein et al., 2021)
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The prescription medication has a list price of $1,027.51 per month, which equals about $256.88 weekly or up to $12,330.12 annually, and that amount is the same for all doses of the drug (0.25 mg, 0.5 mg, 1 mg, 2 mg)