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In the current HepG2 cell model, in which prolonged exposure is not feasible, the use of relatively high QI concentrations in a short timeframe allows for the identification of underlying mechanisms and pathways, as has been done previously in similar studies with hepatic toxicants (Tafazoli and OBrien, 2009

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Detoxification BOX CONTAINS: 1

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10.2147/NDT.S188340 203 HuangY.-Y.GanY.-H.YangL.ChengW.YuJ.-T

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Do not exceed the recommended daily dose

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10.1016/j.neuroscience.2009.03.019 Neuroscience 25 GonzalezA.HydeE.SangwanN.GilbertJ

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