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GLP-1 receptor agonists (GLP-1RA) effectively reduce glycated haemoglobin (HbA1c), lower body weight and provide cardiovascular risk reductions 5,6

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Management strategies: Eat smaller, more frequent meals Avoid high-fat, greasy, or heavily spiced foods initially Stay hydrated For constipation (common): increase fiber gradually, drink more water, consider magnesium supplement Ginger or peppermint tea for nausea Dont lie down immediately after eating (helps with reflux) Under-eating risk (serious for women over 40): The appetite suppression can be so strong that some women struggle to eat enough protein and calories to support muscle maintenance and basic metabolic function

[6] [10] Elevated IGF-1 levels tesamorelin's US Prescribing Information recommends monitoring of IGF-1 during treatment