Published literature documents stimulation of fibroblast proliferation, collagen and elastin synthesis, antioxidant gene upregulation, and modulation of transforming growth factor-beta signaling
52,54-56 A three-month study of a supplement containing a mixture of curcuminoids (at 0.43 mg per 1,000 kilocalories in the diet) plus hydrolyzed collagen and green tea extract in 42 adult dogs with osteoarthritis found the supplement did not improve lameness or owners subjective assessment of mobility, but significantly reduced veterinarians subjective assessment of pain upon movement of affected limbs
We cover the B12 side in more depth in our guide to MIC B12 injections and weight loss shots
Pinealon supplementation helps improve mental performance, stabilize mood, and support long-term cognitive resilience
[DOI] [PubMed] [Google Scholar] 138.Costa A., Ai M., Nunn N., Culotta I., Hunter J., Boudjadja M.B., Valencia-Torres L., Aviello G., Hodson D.J., Snider B.M., et al
7) Liver Dysfunction In a study on over 1,600 adults, high TMAO levels were associated with more severe liver damage and non-alcoholic fatty liver disease [33]
