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Safety & Tolerability Generally well tolerated in studies

Frame it accurately: the approved indications relate to type 2 diabetes, cardiovascular risk, weight management and MASH, not to autoimmune disease

R152 and active site residues C46, K48, Q81, and W136 are highlighted and shown as sticks

While that is part of the answer, new research points to a bigger mechanism at play

What Is Ischaemic Optic Neuropathy

Treatment of rats with colitis using sulforaphane reduces NO and MDA levels, accompanied by increased GPx and reduced glutathione levels, demonstrating its therapeutic antioxidant properties ( Supplementary Table 1 )