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Focusing on strength training becomes especially important to maintain muscle while losing fat

However, significant challenges remain, including the synthesis of stable tripeptides with good tissue penetration, insufficient understanding of their mechanisms of action, the scarcity of studies in larger animal models and human trials, and the lack of direct head-to-head comparisons with larger peptides [75, 95]

GF mice display disrupted BBB integrity, characterized by reduced tight junction protein expression and increased permeability, underscoring the essential role of the microbiota in barrier homeostasis [231]

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