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Naunyn Schmiedebergs Arch Pharmacol 397:87078723
These mutations alter the activity of the encoded enzymes such that instead of converting isocitrate to 2-oxoglutarate (-ketoglutarate), while also generating NADPH, the mutant IDH enzymes reduce 2-oxoglutarate (-ketoglutarate) to 2-hydroxyglutarate (2-HG) while simultaneously oxidizing NADPH to NAPD +
Youll need to come back the next day (or Monday if your appointment is on a Friday) to allow your surgeon to examine the incisions and ensure proper healing
Catching it early helps treat it faster and prevents it from getting worse
For technically demanding anatomy (periorbital, perioral, brow), revision work after another clinic, asymmetry correction, or any patient with unusual facial structure or previous surgery the surgeons anatomical depth becomes meaningful and the difference in outcome is significant