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Questo lavoro, utilizzando la tecnologia dei microarray del DNA (Connectivity Map), ha identificato le vie di segnalazione modulate dal peptide, aprendo nuove prospettive terapeutiche nei campi della fibrosi polmonare, delle malattie neurodegenerative e dell'oncologia

Ovarian cancer-derived extracellular vesicles (OV-EVs) promote cancer progression and angiogenesis primarily by inducing the polarization of macrophages into the M2 phenotype, which is associated with tumor growth and tissue repair

Modifier JW: Used to report medicinal waste from single-dose vials or single-use packages

This is an acyclic deoxyguanosine nucleoside analogue [41]

The affinity-purified shelterin was then subjected to multiple rounds of SEC, using a Superose 6 Increase 10/300 column equilibrated with the SEC buffer (50 mM HEPES pH 8.0, 300 mM NaCl, 5% glycerol, 1 mM TCEP) to further purify and polish the complex

doi: 10.1212/01.wnl.0000325581.26991.f2