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In addition, since cysteine levels in the bone marrow where stress erythropoiesis occurs in SCD patients are unavailable, as a surrogate, we determined cystine levels in SCD mouse spleen, where stress erythropoiesis occurred

Here is the honest evidence status up front, because it shapes everything that follows: the human data on this combination is essentially non-existent

doi: 10.1210/endrev/bnae019 26 WolffJChaikoffIL

Very rarely, individuals might have an allergic reaction symptoms would include hives, difficulty breathing, or swelling of the face and throat