376 GLP-1RAs in Enhancing Exercise Endurance Studies indicate that acute exercise and short-term endurance training significantly increase GLP-1 secretion in mice
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doi:10.1007/s11064-010-0217-0
Bhattacharyya A, Chattopadhyay R, Mitra S, Crowe SE
Safety concerns : Important risks associated with GLP-1 receptor agonists include pancreatitis, gallbladder disease, dehydration leading to acute kidney injury, hypoglycaemia (when used with insulin or sulfonylureas), and potential worsening of diabetic retinopathy with rapid glycaemic improvement
Some patients may have latent autoimmune diabetes in adults (LADA) or other forms of diabetes requiring insulin therapy