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In Vivo Study Taking into consideration the results from the series of screening studies above, Compound 1.70 was selected for in vivo study as it showed retention in activity with all of the key enzymes (GST, GPx, and GR) while also displaying improved stability, as opposed to the other compounds that had lost activity with one or more key enzymes

Research has identified effects on blood vessel formation, growth factor expression, nitric oxide production, and cellular signaling cascades

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Specifically, mitochondrial complex I is believed to be the main component of mitochondria affected in PD as Complex I of the electron transport chain is left vulnerable to oxidative damage ( 3.4 Multiple sclerosis Multiple sclerosis (MS) is a chronic autoimmune disease that affects the CNS