Metabolic Research Collection
doi:10.2174/157015909787602788 Kappos L, Gold R, Miller DH, Macmanus DG, Havrdova E, Limmroth V, Polman CH, Schmierer K, Yousry TA, Yang M, Eraksoy M, Meluzinova E, Rektor I, Dawson KT, Sandrock AW, ONeil GN, BG-12 Phase IIb Study Investigators (2008) Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study
In the solubility-based formulation, a decreasing dilution ratio results in less organic solute dissolved in the aqueous phase, thus decreasing the effective value
People with Fitzpatrick skin types IV-V typically need 4-6 months of consistent treatment to see noticeable changes
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