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Serotonin is synthesized from the amino acid tryptophan in a series of chemical reactions, of which the rate-limiting step is catalyzed by the enzyme tryptophan hydroxylase [178, 179], wherein SAMe functions as a methyl-donating cofactor in the rate-limiting step in these synthetic reactions to increase the levels of this neurotransmitter

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Introduction Recently, a new consensus statement has been published by a group of UK scientific societies regarding the perioperative management of adult patients taking GLP1 receptor agonists (GLP1 RAs), GIP agonists, and SGLT2 inhibitors

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