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10.1172/jci.insight.170671 21 CusiK

When in doubt, involve the prescriber early and favor simple checks such as TSH, free T4, or INR

A 2024 randomized controlled trial (RCT) with 60 women (ages 40-65) applied 0.1% GHK-Cu cream twice daily for 12 weeks, yielding 31% wrinkle reduction (visia analysis) and 28% improved skin elasticity versus placebo (Kim et al., 2024)