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Key points Phentermine is a daily pill prescribed as a short-term appetite suppressant Wegovy (semaglutide) is a weekly injection that mimics natural hormones to support longer-term weight management In clinical trials, Wegovy generally leads to greater weight loss than phentermine Though affordable, phentermine's stimulant properties restrict it to short-term use Prescription weight-loss medications have changed significantly in recent years

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Disruption of Slc52a3 gene causes neonatal lethality with riboflavin deficiency in mice

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The Phase 3 double-blind, randomized, placebo-controlled OASIS 3 trial also demonstrated reduced VMS at 12 weeks compared to placebo (primary endpoint) and the VMS reductions were maintained for up to 52 weeks. In clinical trials, elinzanetant was administered orally once daily