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Oct 2 2019;91(3)doi:10.4081/aiua.2019.3.139
Melatonin acts in synergy with hypothermia to reduce oxygen-glucose deprivation-induced cell death in rat hippocampus organotypic slice cultures
Bioavailability data are from the PIONEER program [10]
Allicin supplementation significantly decreased serum TMAO in -carnitine-fed C57BL/6 J mice, reduced aortic lesions, and altered the fecal microbiota in carnitine-induced, atherosclerosis-prone, apolipoprotein E-deficient (ApoE / ) mice
This mechanism has been validated in RCTs in populations including older adults, hemodialysis patients, and schizophrenia patients on maintenance medication
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