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for approximately 16 weeks) results in anxiety and anhedonic behaviors, and 4 months of HFD consumption results in increased levels of corticosterone and blood glucose, which also activate the innate immune system, increasing the release of inflammatory cytokines (i.e., IL-6, IL-1, TNF-)

Eapen, MD, notes, Dosage must not be increased by more than 2.5 mg at a time, and keeping a minimum of 4 weeks between dose changes is recommended

Genetic variations in growth factor receptors and peptide metabolic pathways affect individual responsiveness