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They're taking a lot less than the kind of standard clinical trials will be

A four-probiotics regimen combined with a standard Helicobacter pylori -eradication treatment reduces side effects and increases eradication rates

Minimally invasive decompression versus open laminectomy for central stenosis of the lumbar spine: pragmatic comparative effectiveness study

In light of this, we propose a set of recommendations for clinical practice (Figure 1), which are informed by these observations and take into account critical patient characteristics

Two neurocognitive domains identified for patients with myalgic encephalomyelitis/chronic fatigue syndrome and post-acute sequelae of COVID-19