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Spontaneous postsynaptic currents (PSCs) were recorded using single cell patch-clamp electrophysiology to monitor the activity of the networks grown for 8~10 days in Control and BDNF-treated cultures

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In addition, elecoglipron showed clinically meaningful improvements in several exploratory analyses of cardiometabolic risk factors including lower blood pressure and C-reactive protein levels, a marker of systemic inflammation

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Ozempics success for obesity treatment prompted other drug makers to formulate their own version of GLP-1 receptor agonists

Practical considerations: Growth hormone peptide protocols require months for musculoskeletal benefits versus weeks for direct-acting peptides (BPC-157, TB-500)