By mimicking the hormone GLP-1 (glucagon-like peptide-1), semaglutide helps regulate blood sugar levels and appetite, leading to weight loss in some individuals
FDA Safety Context for Compounded GLP-1 Medications in 2026 Quick Answer: Compounded GLP-1 medications are not FDA-approved and are not reviewed by FDA for safety, effectiveness, or quality before marketing
Ozempic and Wegovy both contain semaglutide, which is a type of drug known as a GLP-1 agonist
Semaglutide works by reducing appetite, slowing digestion, and helping the body use insulin more effectively
At the molecular level, GLP-1 receptor activation increases intracellular cyclic AMP (cAMP) through the Gs protein signaling pathway
European Review for Medical and Pharmacological Sciences, 19 (10), 19221940