The iron chelators deferoxamine mesylate and VITE could change these circumstances by increasing GPX4 expression and decreasing iron overload [90]
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Compelling evidence also demonstrates that HIV-1 related proteins (e.g., HIV-1 envelope glycoprotein 120) and RNAs from infected cells act as potent pro-inflammatory stimuli, triggering neurotoxic microglial activation [14, 15]
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