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[18] [19] Patients should be instructed to report emergent suicidal thoughts or behaviors, and the medication should be discontinued if these occur

Unlike glutathione sublingual or IV therapy, topical forms may not penetrate deeply enough to provide full-body benefits

In patients with alcohol dependence, visual alcohol cues were found to increase anticipatory reward responses in distributed brain clusters, including ventral striatum during their first 21 days of controlled abstinence (Koopmann et al., 2019)

Reported side effects from topical application are generally mild

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Recent clinical evidence further supports the synergistic interaction between CIT supplementation and exercise on vascular and muscle adaptations in aging populations (34)