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Improves oxygen uptake during exercise

137 and in B cells and neutrophils, it controls cytokine expression, migration, and lifespan, collectively preserving hepatic immune homeostasis

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Patients with pre-existing GERD, hiatal hernia, or obesity (a common indication for semaglutide) may be more susceptible to reflux symptoms

This effect may be mediated by inhibiting Wnt-driven epithelial proliferation and dysfunction, and by correcting solute transport disorders that control the physiological balance of the Na + /Cl - (decreased fecal Na + and Cl - levels, increased serum Na + and Cl - levels), and reducing serum total protein [87,88,89]