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Oxidative stress is present in the early stages of CKD, contributing to renal function deterioration with increased antioxidant consumption and ROS generation [38, 39]

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doi:10.1146/annurev-food-111523-122028 Gibson A, Woodside JV, Young IS, et al

Dysfunction of ABCG2 plays a significant role in pediatric-onset hyperuricemia and gout [22]

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The peptide has been studied extensively in animal models since the 1990s, with over 100 published research papers examining its effects on various tissues and conditions