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Diagn Pathol

Probiotic administration reduces intestinal leakage by, among others, affecting intestinal immunoregulation and anti-inflammatory effects (for example, an increase in sIgA production), anti-inflammatory effects, strengthening the epithelial barrier (for example, an increase in the synthesis of mucin and short-chain fatty acids (SCFAs), and the production of bacteriocins, which limit the growth of pathogenic microorganisms (for example, defensin) [8, 133, 134]

Additionally, SS-31 has been shown to reverse the mitochondria fragmentation (Machiraju et al., 2019)

No clinical trial has tested this specific combination, but the theoretical basis for synergy is compelling

visible improvements in skin texture, fine lines, and elasticity begin to emerge

Hoffman, A