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Choosing a GLP-1R agonist is mostly based on what the patient wants
Data on tirzepatide in fatty liver disease Within a substudy with 296 participants of the SURPASS-3 trial (SURPASS-3 MRI), changes in liver fat and other fat compartments were monitored during the study, and a subgroup of the tirzepatide cohort was compared to the insulin degludec comparator subgroup (54, 79)
model was observed (Fig
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Effects when activated: Stimulate insulin secretion from pancreatic beta cells Promote fat storage in adipose tissue Enhance bone formation May have effects on cognitive function and neuroprotection Key Differences: Hormone specificity: GLP-1 receptors are activated by GLP-1, while GIP receptors are activated by GIP
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