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No antibody formation observed
Heres why: Ongoing Absorption Issues: Many people have conditions that impair their ability to absorb B12 from food or oral supplements, such as pernicious anemia or gastrointestinal disorders
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This mechanistic distinction means the compound could theoretically be combined with appetite-suppressing peptides for a protocol that simultaneously reduces energy intake (GLP-1) and restores adipocyte energy expenditure (NNMT inhibition) though this remains purely theoretical without published combination data
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