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Remodeling the ECM through targeted nutrition could enhance explosive-force generation and reduce susceptibility to the overuse injuries that plague distance athletes.11 For the endurance coach or practitioner building periodized nutrition plans, collagen peptides represent the lowest-risk, highest-evidence peptide option

10.1016/j.jmb.2007.01.038 398 MarshJ

Peptides act as messengers (signalling molecules) that send signals to cells and tissues of the body to regulate their functions, such as releasing insulin, burning fat, or delaying digestion

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A useful overview of that link is in microbiota-immune, which explains how microbes steer immune behavior