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As the number of diabetic patients continues to grow globally, this disease has become a major and growing challenge in global public health

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Although the progression of neurologic complications is generally gradual, such symptoms may not be reversed with treatment of vitamin B 12 deficiency, especially if they have been present for a long time

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This method resulted in the selective expression of hM3D-mCherry in LS GLP-1R neurons (Figure 5A)