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Chiang and his colleagues, on the other hand, reviewed 48 randomized controlled trials with a combined 94,245 patients who had Type 2 diabetes, overweight or obesity
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10.1186/s13075-018-1699-4 102 MisawaK.HasegawaT.MishimaE.JutabhaP.OuchiM.KojimaK.et al (2020)
Orforglipron's demonstration that a small molecule could achieve clinically relevant GLP-1 receptor activation upended this assumption and opened a new chapter in incretin-based therapeutics
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GLP-1 analogs also reduced systolic and diastolic blood pressure and total cholesterol levels [32]
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