They increase oxidative stress, damage cellular structures, and promote the fibrotic changes associated with permanent hair loss
Addition of DHT and finasteride to DPCs demonstrates the interaction between androgen and Wnt/-catenin Since the crosstalk between androgen and Wnt/-catenin pathway plays a pivotal role in the regulation of hair growth, the effects of DHT and finasteride on the levels of AR and -catenin were examined in the DPCs
Use the top edge of the plunger stopper to measure the dose accurately
These findings further improved the function of FGF5 gene, and provided therapeutic ideas for androgen alopecia
Nonetheless, it is important to highlight the high heterogeneity and limitations of the studies, such as (1) low to moderate methodological quality, (2) variation in a selected population, (3) a lack of inclusion and evaluation in different skin types, (4) small sample sizes, (5) variable designs, (6) types of chemical peels, (7) deficient efficacy measures, (8) short-term or no follow-up, (9) attrition rate, (10) heterogeneities in the grouped results, and (11) poor conclusions
Psychiatry 18 , 582594 (2013)
