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They are provided strictly for research purposes only and must not be used outside approved laboratory protocols.

More studies are needed to explore whether the GPX4-mediated activation of parthanatos is a widespread mechanism in other disease models, and how the lipid peroxidation involved in the regulation of parthanatos

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For context, CagriSema's GI rate was compared to its individual components: semaglutide alone and cagrilintide alone both had lower GI event rates than the combination, consistent with additive GI effects

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