Glutathione and homoglutathione play a critical role in the nodulation process of Medicago truncatula
In streptozotocin-induced diabetic mice, metformin has been shown to significantly improve sperm count, testicular proliferation, and testosterone levels, which may depend on elevated leptin levels and the expression of its receptor Ob-R in the testis of mice after administration of metformin (Annie et al
Raj GM, Raveendran R (2019) Introduction to basics of pharmacology and toxicology: volume 1: general and molecular pharmacology: Principles of drug action
Moreover, structural superposition between GSH-bound OsDHAR and glutathione disulphide (GSSG)-bound hGSTO1-1 showed dramatic helix (5, 6 and 9) movement in the C-terminal domain region of OsDHAR, which likely allows bound GSH molecules in the G- and H-sites to be sufficient close for GSSG formation (Supplemental Fig
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