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This triple-receptor activity distinguishes retatrutide from earlier incretin mimetics such as semaglutide (a pure GLP-1 agonist) and tirzepatide (a dual GIP/GLP-1 agonist)

Approval is expected in 2026 or 2027 depending on trial results and FDA review

Patient safety and product quality is very important to us

GLP-1 side effects (nausea, vomiting, constipation, diarrhea) are typically gastrointestinal and dose-manageable, resolving as your body adjusts

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Patients received 1,000 milligrams of a long-acting testosterone drug, called undecanoate, on the first day of the study, at week six, and then every three months