Alpha lipoic acid (ALA) is a sulphur-containing antioxidant, which occurs naturally, in small amounts, in such foods as spinach, broccoli, beef, yeast, kidney, and heart
"Hives occur when the skin comes into contact with any form of water, which includes bathing but also sweat, tears, and rain." The exact cause isn't known, but it's possible there's a chemical or allergen in the water that's problematic for those with this condition
intranasal doses of approximately 120 mcg/kg used in animal research Timing: Evening administration, typically 30 to 60 minutes before intended sleep Onset: Sleep pressure reported within approximately 130 minutes of administration in human studies Duration: Effects on sleep architecture observed with both single doses and multi-day protocols Regarding cycling, the evidence is mixed
Subanalysis of a clinical trial
over-the-counter creams and suppositories may offer temporary alleviation, but they rarely address the underlying inflammation or provide lasting comfort
The problem: very short half-life (~50 minutes) and 3 daily injections at meals , an extremely impractical regimen
