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Similarly, alcohol and over-the-counter pain relievers like acetaminophen are heavily metabolized by the liver and rapidly deplete the body's natural glutathione stores

The strengths of the reviewed case reports include available data on liver enzymes before and after starting statin therapy as well as follow-up laboratory findings after cessation of statin use in all but two cases

doi:10.1016/j.jsbmb.2019.105497

Polycythemia vera, hereditary cyanide deficiency (Leber optic neuropathy), and allergy to cobalt or cyanide are contraindications