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The regain tends to be gradual at first, then accelerates as appetite signals return to pre-treatment patterns
The US Food and Drug Administration approved this first-in-class medication for the management of type 2 diabetes (T2D) in 2022 [2], for the reduction of excess weight in adults with obesity or overweight in 2023 [3], and for moderate-to-severe obstructive sleep apnea (OSA) in people with obesity in 2024 [4]
B12 is added because it directly supports red blood cell formation, neurological function, and steady daily energy
This attrition is what scientists call the Hayflick limit, named after Leonard Hayflick, who discovered that normal human cells divide roughly 4060 times before stopping [23]
The session highlighted concerns that: Appetite suppression may mask eating disorder symptoms Weight loss may be misinterpreted as clinical improvement Binge eating disorder may be misdiagnosed, particularly in larger-bodied individuals It is necessary to emphasize the importance of careful screening and ongoing assessment
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