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Elevated levels of ROS and oxidative damage markers, such as 8-OHdG and MDA, have been detected in the synovial fluid and tissues of RA patients

The clock starts ticking

Herrmann W, Obeid R

MFG-E8 alleviates intervertebral disc degeneration by suppressing pyroptosis and extracellular matrix degradation in nucleus pulposus cells via Nrf2/TXNIP/NLRP3 axis

Treatment of p47phox knockout animals with DOCA-salt markedly reduced levels of oxidative stress and abolished superoxide reducing effects of NOS inhibition compatible with a prevention of eNOS uncoupling

A role for glutamate decarboxylase during tomato ripening: the characterisation of a cDNA encoding a putative glutamate decarboxylase with a calmodulin-binding site