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The primary outcome (a composite of cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, or hospitalization for unstable angina) occurred in 839 patients in the sitagliptin group (11.4%) and 851 patients in the placebo group (11.6%), which was not significantly different

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Our data showed that increased oxidative stress and mitochondrial dysfunction were involved in the pathogenesis of Fabry disease and were not fully eliminated even with ERT