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Table 1) Sleep abnormalities Individuals with PWS have sleep-disordered breathing, including central and obstructive sleep apnea, abnormal arousal, abnormal circadian rhythm in REM sleep, reduced REM latency, and abnormal response to hypercapnia 26, 27 as well as excessive daytime sleepiness

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By bridging disciplinary silos and employing innovative pharmacotherapies, the study charts a hopeful course for women contending with the multifaceted challenges of PMOS