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We cannot promise that the transition will be effortless, but we can promise to walk with patients through the anxiety, to support any side effects, and to help them plan for continuity of nutrition, exercise and behaviour change during the process

However, similar to GnRH agonist, GnRH antagonist is associated with hypoestrogenic adverse effects, which require the addition of estradiol and norethindrone acetate (add-back therapy) to attenuate the hypoestrogenic effect (Schlaff et al., 2020)

Furthermore, GLP-1 exhibits significant cardioprotective properties, particularly in pathological conditions, such as ischemia and myocardial damage

The risk profile depends heavily on drinking frequency and amount consumed

In the osteoarthritis trial, participants lost up to an average of 71.2 pounds

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