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12 The impact of these additional five years due to PTA and PTE is profound: Novo Nordisk is projected to earn an estimated $166 billion from Ozempic and Wegovy as a result of this extended period of patent protection, which spans from March 2026 to December 2031

In cohort studies SGLT2 inhibitors were associated with a two-fold increased risk of EDKA as compared with GLP-1RAs

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However, the effect of GLP1R agonists on LVH induced by pressure overload is still unclear