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Randomisation in these trials was stratified by baseline background medication
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Executive dysfunction
Cagrilintide, a long-acting human amylin analogue, exerts both central and peripheral effects by enhancing satiety, delaying gastric emptying, and modulating postprandial glucagon secretion, whereas semaglutide acts on GLP-1 receptors in the central nervous system and peripheral tissues to regulate appetite, glycemic control, and energy balance