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It works by simultaneously activating three incretin-related receptors: the glucagon-like peptide-1 (GLP-1) receptor, the glucose-dependent insulinotropic polypeptide (GIP) receptor, and the glucagon receptor

All of this matters because the brain, as we now know, has its own GLP-1 system, parallel to and largely separate from whatever is going on in the gut

doi: 10.1111/1462-2920.13589 53 PrydeSEDuncanSHHoldGLStewartCSFlintHJ

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What should be responsible for eryptosis in chronic kidney disease