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Description

ARA290, a nonerythropoietic peptide engineered from erythropoietin, improves metabolic control and neuropathic pain in spontaneous type 2 diabetes

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The gastrointestinal system is highly integrated with the central nervous system (CNS)

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For an intravenous dose, bioavailability is assumed to be equal to unity

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This can be achieved using antiangiogenic agents which promote vascular normalization [28, 29]

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Biochemical assessments of peripheral blood from AD patients demonstrated significantly elevated levels of the mitochondrial fission factor Fis1, with postmortem brain specimens further revealing upregulated Drp1 expression in AD cases (Pakpian et al., 2020)

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