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As a key regulator of inflammatory cell death, ROS have recently been found to affect GSDMDs palmitoylation through various mechanisms

Epigenetic changes may also underlie epithelial barrier leakage

Cell culture and transfection Gastric cancer cell lines SNU638 (KCLB No.00638), SNU216 (KCLB No.00216), and SNU668 (KCLB No.00668) cells were obtained from KCLB (Korean Cell Line Bank), and HEK293T (CRL-3216) cells were obtained from ATCC (American Type Culture Collection)

4, lower panel), which indicated diminished tinnitus-like deficits, the efficacy of NHPN-1010 versus vehicle treatment was demonstrated by two key findings: (1) NHPN-1010 treatment resulted in an increase in IHC ribbon counts (Fig