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[PubMed] [Google Scholar] Fani M
Research examining human cardiac samples has revealed several key findings: GLP-1R mRNA transcripts have been consistently detected in all four cardiac chambers from human hearts, at levels approximating those in human pancreas [1] Receptor expression is notably absent in cardiac fibroblasts, coronary artery endothelial cells, and vascular smooth muscle cells according to some studies [1] Human GLP-1R expression appears predominantly in cardiomyocytes, albeit at relatively low levels [2] Interestingly, species differences exist in GLP-1R distribution patterns
Glucocorticoid-mediated effects are influenced by both hormone bioavailability and tissue-specific responsiveness
Yang, Y., Huycke, M
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