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doi: 10.1016/j.heliyon.2021.e08013 63 NishidaK.KondoA

The affected area may feel firm or rubbery under the skin

Naevomelanocytes may originate from melanocyte precursors that have acquired some genetic alterations during development, consequently preventing them from differentiation into mature functioning melanocytes in the basal cell layer of the oral epithelium

117 XieY.HouW.SongX.YuY.HuangJ.SunX.et al (2016)

41,87 Inactivation of CDKN2A is detected in PanIN-2 lesions, whereas mutations in TP53 and SMAD4 are found late in PDAC progression